Publications 

Publications:

Fc Optimization of Therapeutic Antibodies Enhances Their Ability to Kill Tumor Cells In vitro and Controls Tumor Expansion In vivo via Low-Affinity Activating Fc Receptors - Jeffrey B. Stavenhagen, Sergey Gorlatov, Nadine Tuaillon, Christopher T. Rankin, Hua Li, Stephen Burke, Ling Huang, Syd Johnson, Ezio Bonvini and Scott Koenig Cancer Research.  2007 Sep 15; 67 (18): 8882-90.

Monoclonal antibodies capable of discriminating the human inhibitory Fcgamma-receptor IIB (CD32B) from the activating Fcgamma-receptor IIA (CD32A): biochemical, biological and functional characterization - Veri, M.C., Gorlatov, S., Li, H., Burke, S., Johnson, S., Stavenhagen, J., Stein, K. E., Bonvini, E., Koenig, S. Immunology.  2007 Jul; 121 (3): 392-404.

CD32B, the human inhibitory Fc- receptor IIB, as a target for monoclonal antibody therapy of B-cell lymphoma - Rankin, C.T., Veri, M.C., Gorlatov, S., Tuaillon, N., Burke, S., Huang, L., Inzunza, H.D., Li, H., Thomas, S., Johnson, S., Stavenhagen, J., Koenig, S., and Bonvini, E. - Blood. 2006 Oct 1;108(7):2384-91.

Development of a humanized monoclonal antibody with therapeutic potential against West Nile Virus - Oliphant, T., Engle, M., Nybakken, G.E., Doane, C., Johnson, S., Huang, L., Gorlatov, S., Mehlhop, E., Marri, A., Chung, K.M., Ebel, G.D., Kramer, L.D., Fremont, D.H., and Diamond, M.S. - Nature Medicine. 2005 May;11(5):522-30.

Structural basis of West Nile virus neutralization by a therapeutic antibody - Nybakken, G.E., Oliphant, T., Johnson, S., Burke, S., Diamond, M.S., Fremont, D.H - Nature. 2005 Sep 29;437(7059):764-9.

Activating and inhibitory IgG Fc receptors on human DCs mediate opposing functions - Boruchov, A.M., Heller, G., Veri, M.C., Bonvini, E., Ravetch, J.V., and Young, J.W. - J. Clin. Invest. 2005 Oct; 115(10):2914-23.

Selective blockade of inhibitory Fc receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells - Dhodapkar, K.M., Kaufman, J.L., Ehlers, M., Banerjee, D.K., Bonvini, E., Koenig, S., Steinman, R.M., Ravetch, J.V., and Dhodapkar, J.V. -  Proc. Natl. Acad. Sci. USA. 2005 Feb 22;102 (8):2910-5.