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Partnering

MacroGenics is pursuing alliances to participate in development of its proprietary product candidates and technology platforms.

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Product Pipeline

MacroGenics has a diverse portfolio of product candidates with several clinical trials currently underway or planned for the near future.  Set forth below is the company's development pipeline.

 

Program (Target) Indication Partner Lead Optim. Pre-Clin. Phase 1 Phase 2 Phase 3
ONCOLOGY          
MGAH22 * (HER2) Metastatic Breast *  *  *  *  * 
Solid Tumors *  *  *  *  * 
MGA271 ** (B7-H3) Solid Tumors *  *  *  *  * 
MGD006 **  Hematologic *  *  *  *  * 
MGD007 **  Gastrointestinal *  *  *  *  * 
Two DARTs   Solid Tumors *  *  *  *  * 
Multiple DARTs   Various *  *  *  *  * 
mAbs/DARTs  (>75 Targ.) Solid & Liq. Tumors *  *  *  *  * 
AUTOIMMUNE          
Teplizumab  (CD3) T1D - At-Risk (NIH) *  *  *  *  * 
DART  (CD32B x CD79B) SLE, RA *  *  *  *  * 
Multiple DARTs   Autoimmune *  *  *  *  * 
INFECTIOUS DISEASES          
Mult. mAbs/DARTs   Emerging Diseases *  *  *  *  * 

*Green Cross has marketing rights in Korea only.

**MacroGenics retains rights in U.S., Canada, Mexico, Japan, Korea & India.
Servier has option to license rights in ROW.
Major Rights Retained
Partnered Globally